US5588681057
US5588681057
Madrigal Pharmaceuticals, Inc.
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Company Profile
Madrigal Pharmaceuticals, Inc., a biopharmaceutical company, focuses on delivering novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH) in the United States. It offers Rezdiffra, a liver-directed thyroid hormone receptor beta agonist for treating MASH. The company was founded in 2016 and is headquartered in West Conshohocken, Pennsylvania.
Latest News

Simply Wall St. • 10/08/2026
Madrigal Pharmaceuticals (MDGL) Genetics Update Keeps Fair Value In Focus

Simply Wall St. • 10/08/2026
Madrigal Pharmaceuticals (MDGL) Stock Trades At A Discount Following A Very Large 5 Year Run

Simply Wall St. • 10/07/2026
Is Rezdiffra’s Genetic-Risk Agnostic Data Reframing The Investment Case For Madrigal Pharmaceuticals (MDGL)?

Zacks • 10/07/2026
Can NVO's Semaglutide Push Create Growth Beyond Cardiometabolic Care?
MT Newswires • 09/23/2026
Citigroup Initiates Madrigal Pharmaceuticals at Buy With $725 Price Target
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Key Metrics & Overview
Detailed metrics & financial data of the company
Company Profile
5
MetricsCountry
Region
Sector
Industry
Website
🛡️ Risk & Structural Analysis
Multi-Factor Risk Model & Market Data
7/7 Very High
5Y Volatility
133.4% p.a.
Max Drawdown (5Y)
-61.4%
Sharpe Ratio (5Y)
0.30
Beta Factor
-1.05
Size Class
Large Cap
Notes & Warnings
Single Stock Risk: Investing in an individual stock carries full company and insolvency risk (no fund diversification).
Unprofitable business model: The company is currently generating net losses.
🔴 High valuation risk: Avg P/E of 49.0 (Elevated multiple compression risk)
🔴 Low analyst coverage – higher uncertainty in growth estimates & projections
Structurally High Volatility: Above-average fluctuations persist across 5 to 10 years (133.4% p.a.).
Historical Stress Test: Maximum peak-to-trough drawdown of -82.2% in the extended horizon.